Job Details  

Student Computational Biology Research Assistant
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Job ID 37891
Employer Cancer Center, Yale
Employer Type On Campus
Category Research
Job Type On-Campus Jobs
Job Description

Exceptional Opportunity: Computational Biology Research Assistant in Gastrointestinal Cancer Research

Are you passionate about leveraging computational approaches to transform cancer research? Join our dynamic translational research team and apply cutting-edge bioinformatics, spatial biology analysis, and image analysis to advance our understanding of gastrointestinal malignancies!

What You'll Do:

• Analyze spatial biology data to map tumor architecture and microenvironment interactions in GI cancers • Develop and apply computational pipelines for multiplexed imaging analysis, spatial profiling, and single-cell sequencing • Process multiomic datasets (genomics, transcriptomics, proteomics, metabolomics) to uncover novel therapeutic targets • Apply machine learning and computer vision approaches to extract biological insights from tissue imaging and high-dimensional molecular data • Integrate spatial, imaging, single-cell, and molecular data to identify actionable drug targets and biomarkers • Collaborate directly with clinicians and dry-lab researchers to translate clinical questions into computational analyses • Build analytical workflows for diverse high-throughput and high-content datasets

What You'll Gain:

This role offers unparalleled exposure to the intersection of computational biology, spatial omics, imaging analysis, and translational cancer medicine. You'll develop critical skills in:

  • Spatial transcriptomics and proteomics data analysis and visualization
  • Computational image analysis of multiplexed tissue imaging (IF, IHC, spatial omics platforms)
  • Single-cell sequencing data processing and interpretation
  • Integration of spatial, imaging, single-cell, and molecular data for biomarker development
  • Advanced bioinformatics analysis of cancer genomics and multiomic data
  • Computational drug discovery and target identification workflows
  • Scientific communication at the interface of computation and biology
  • Building networks with computational biologists, pathologists, clinicians, and cancer researchers

Perfect For Students With Expertise In:

Computational Biology • Bioinformatics • Biomedical Imaging/Image Analysis • Data Science (with biology focus) • Quantitative Biology • Systems Biology • Biomedical Informatics • Computer Vision (applied to biology) • Cancer Genomics

Why This Matters:

Your computational analyses will directly inform precision oncology approaches for gastrointestinal cancer patients—bridging spatial data, molecular profiling, imaging, and bedside care. This experience provides exceptional preparation for graduate programs in computational biology, careers in cancer genomics, pharmaceutical/biotech industry roles, or physician-scientist pathways.

 

Job Requirements

Requirements:

Essential: • Current enrollment as an undergraduate or graduate student with computational biology, bioinformatics, quantitative biology, or biomedical imaging background • Proficiency in programming (Python, R, or similar languages) • Strong foundation in statistics and data analysis • Experience with biological data analysis (genomic, imaging, spatial, or single-cell data) • Excellent attention to detail and ability to handle large, complex datasets • Strong written and verbal communication abilities • Ability to work independently and as part of a collaborative team • Commitment to maintaining patient confidentiality and research ethics

Highly Preferred: • Experience with spatial transcriptomics or spatial proteomics platforms and analysis tools • Familiarity with single-cell sequencing analysis (Seurat, Scanpy, or similar) • Experience with image analysis and computer vision applied to biological/medical imaging • Experience with multiplexed imaging analysis (CODEX, IMC, MIBI, Visium, Xenium, CosMx, etc.) • Background in cancer biology or oncology research • Experience with multiomic data integration approaches • Knowledge of drug discovery pipelines or target identification methods • Familiarity with machine learning/deep learning applications in imaging or biology • 

What We Provide:

• Mentorship in translational computational cancer research • Access to rich spatial biology, imaging, single-cell, and multiomic datasets from GI cancer patients • Training in state-of-the-art spatial biology, image analysis, and bioinformatics methods • Opportunities for co-authorship on peer-reviewed publications • Professional development and networking opportunities • Flexible scheduling to accommodate academic commitments

Time Commitment:

• 10-20 hours per week (negotiable based on student availability) • Opportunity for increased involvement during breaks/summer

Ready to apply your computational, spatial biology, and image analysis expertise to advance gastrointestinal cancer research? Join us in discovering the next generation of cancer therapeutics and biomarkers!

Compensation $18.00/hour
Job Level CY26: Level III
Hours 10.0 to 20.0 hours per week
Primary Contact Raghav Sundar
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